Clouds come in different shapes and sizes.
Meaning: Clouds can have different outlines and measurements, which makes them look different from each other.
Choice of Words: Come means to arrive or appear. Different means not the same. Shapes are the outlines of objects. Sizes are the measurements of how big or small something is. When you say "clouds come in different shapes and sizes," you are saying that clouds can have different outlines and measurements.
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